Pharmacological action of Vinpocetine

Vinpocetine is a semi-synthetic vincamine derivative. Similar to vincamine, it has a high selective expansion effect on cerebral blood vessels. The pharmacological effects are as follows:
1Vinpocetine can inhibit calcium-dependent phosphodiesterase activity, increase the cAMP content of relaxed vascular smooth muscle, thereby relaxing vascular smooth muscle and increasing cerebral blood flow.
2Vinpocetine can enhance red blood cell deformability, reduce blood viscosity, inhibit platelet aggregation, and improve blood flow and microcirculation.
3 Promote the uptake of glucose by brain tissue and promote the metabolic conversion of monoamine in the brain.
4 In cerebral ischemia, it can inhibit the increase of lactic acid in the brain, increase the content of ATP, inhibit the production of lipid peroxide in the brain, and delay the time of cerebral ischemia and phlegm. Therefore, Vinpocetine can improve brain metabolism and protect brain function.